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AndrologyModerate evidence 11 min read Last reviewed: 2025-02-08

Canine semen cryopreservation, fundamentals

From collection to straw: why post-thaw motility alone is not enough.

Summary

Cryopreservation of canine semen enables long-term storage and international genetic exchange but comes with a well-documented drop in fertility relative to fresh semen. Sound protocols and honest quality metrics matter.

Key evidence
  • Post-thaw progressive motility of at least 50% is a common minimum acceptance criterion for banking.
  • Egg-yolk–based extenders with glycerol remain the most widely used freezing medium.
  • Intrauterine deposition (surgical or transcervical) is required for acceptable fertility with frozen semen.
  • Membrane integrity assessed by fluorescent staining correlates with fertility better than motility alone.
01

The workflow

Collection by manual stimulation, fractional evaluation of the ejaculate, extension in a validated medium, cooling curve, glycerol equilibration, freezing in vapor and storage in liquid nitrogen at -196°C.

02

Quality control

A responsible banking protocol documents pre-freeze and post-thaw motility, morphology, membrane integrity and, ideally, longevity at 37°C. Reports without post-thaw metrics should be considered incomplete.

03

Clinical caveats

Freezing does not fix a suboptimal ejaculate. Fertility work-up and any clinical procedure remain the responsibility of a licensed veterinarian.

References

  1. Linde-Forsberg C. Regulations and recommendations for international shipment of chilled and frozen canine semen. Theriogenology.
  2. Peña AI, Núñez-Martínez I. Canine sperm cryopreservation. Reprod Dom Anim.

Educational information only. Does not replace veterinary consultation. No diagnosis. No prescriptions. No emergency advice.